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References

1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.

2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/

3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf

4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36

5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs

ixie M, Bowers J, Heating K, Well M, Dow Stopper M, 4. Efficacy of tadalafil in the treatment of pulmonary arterial hypertension. Br J Pharmacol 1997; [38] (4) 375.

6. Tadalafil 5mg. [Revised in September 2009] [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536092/

7. Tadalafil 5mg Tablets.https://www.medicines.org.in/emc/files/ppt.1998.یUsers legalizing promoting promoting promoting promoting promoting promoting

8. Branden U. Phytic Formulation.https://www.medicines.org.in/emc/Word/W0038.htm

9.https://www.medicines.org.in/emc/Word/W0039.htm

10. Tadalafil 10mg.https://www.medicines.org.in/emc/Word/W0040.htm

11. Tadalafil 10mg Tablets.https://www.medicines.org.in/emc/Word/W0041.htm

12. Sildenafil 100mg.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640723/

13. brand-name Cialis.https://www.medicines.org.in/emc/Word/W0037.htm

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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
RicanMixOnline.com readers are quick to share their experiences with TopDrug-Food. Plus, they can share their experiences with other drug-food items as well. Please follow the on on and share your information with the online community.
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  • : Cialis can increase the blood pressure by approximately 50%, leading to symptoms like dizziness, lightheadedness, or fainting. It is contraindicated to use Topyl Nitrate with nitrates or alpha-blockers. It is a proton pump inhibitor and should be used with caution in individuals with a history of heart disease or a family history of heart disease.

    : Both Cialis and alpha-blockers can cause increased blood pressure with the effects resembling loss of vision.

    Other antihypertensive drugs (e.g.

    Cialis Professional

    Cialis Professional is a well-known medication that contains tadalafil, a phosphodiesterase type 5 inhibitor, which allows it to relax the blood vessels in the penis. This allows you to achieve firmer, longer-lasting erections and a faster response to sexual stimulation. Cialis Professional has been shown to help men who have erectile dysfunction (ED) and to improve their sexual performance. Its effectiveness is also proven to improve sexual satisfaction, as well as to improve overall quality of life. You can also buy Cialis Professional from a licensed pharmacist, who will provide you with a complete medical history and current medication, as well as provide you with a full and accurate diagnosis.

    How Cialis Professional Works

    Cialis Professional, containing tadalafil, is a phosphodiesterase type 5 inhibitor used to treat erectile dysfunction (ED). It is also known as a phosphodiesterase type 5 inhibitor in the U. S. It works by relaxing the blood vessels in the penis, allowing blood to flow into the penis when sexually excited.

    Cialis Professional Side Effects

    As with any medication, Cialis Professional can cause side effects. Some of the most common ones include headaches, facial flushing, indigestion, nasal congestion, and dizziness. Other less common side effects include:

    • Flushing
    • Headaches
    • Indigestion
    • Nasal congestion
    • Dizziness
    • Stuffy nose
    • Sensitivity of the skin

    Rare but serious side effects include vision problems, priapism (prolonged erection), and sudden hearing loss.

    If you experience any of these side effects, stop taking Cialis Professional and contact a doctor right away.

    Cialis Professional FAQs

    Is Cialis Professional safe?

    Yes, Cialis Professional is generally safe. It has no negative effects on your cardiovascular system and is taken for a certain amount of time before sexual activity. You can have an erection with Cialis Professional and a healthy dose will be recommended.

    Can I buy Cialis Professional without a prescription?

    No, you cannot buy Cialis Professional without a valid prescription from a licensed pharmacist. You will need to consult with a doctor before taking Cialis Professional and they will be able to give you a complete medical history and a complete physical examination to ensure that the medicine is safe for you.

    How long does it take for Cialis Professional to work?

    The effects of Cialis Professional typically start to work within 30 minutes to 1 hour after you take it. It is important to note that you will not feel an erection when you are sexually excited. You can expect to have a hard, spontaneous erection within an hour.

    Can I take Cialis Professional with alcohol?

    No, Cialis Professional can cause excessive alcohol consumption. Alcohol is known to cause side effects. It is advisable to avoid drinking alcohol while taking Cialis Professional and avoid drinking grapefruit juice when you are taking it.

    Are there any side effects of Cialis Professional?

    Some of the common side effects of Cialis Professional include:

      Does Cialis Professional contain nitrates?

      No, Cialis Professional does not contain nitrates, which are found in many prescription drugs. Nitrates are a class of medications that contains the active ingredient tadalafil. They are used to treat chest pain, angina (chest pain), high blood pressure, and heart failure.

      What is the dosage of Cialis Professional?

      The usual starting dose of Cialis Professional is 20 mg, taken orally once a day for 4-5 hours. The dosage is determined based on your medical condition and response to treatment.

      Cialis Professional Reviews

      Many people have reported success in using Cialis Professional.